diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
new file mode 100644
index 0000000..1f3de91
--- /dev/null
+++ b/.pre-commit-config.yaml
@@ -0,0 +1,26 @@
+ci:
+  autoupdate_branch: "main"
+  autoupdate_schedule: monthly
+repos:
+  - repo: https://github.com/PyCQA/flake8
+    rev: 4.0.1
+    hooks:
+      - id: flake8
+        files: "^connexion/"
+        additional_dependencies:
+          - flake8-rst-docstrings==0.2.3
+  - repo: https://github.com/PyCQA/isort
+    rev: 5.10.1
+    hooks:
+      - id: isort
+        name: isort
+        files: "^connexion/"
+        args: ["--project", "connexion", "--check-only", "--diff"]
+      - id: isort
+        name: isort examples
+        files: "^examples/"
+        args: ["--thirdparty", "connexion", "--check-only", "--diff"]
+      - id: isort
+        name: isort tests
+        files: "^tests/"
+        args: ["--project", "conftest", "--thirdparty", "connexion", "--check-only", "--diff"]
diff --git a/README.rst b/README.rst
index b64d12c..f75fde9 100644
--- a/README.rst
+++ b/README.rst
@@ -583,6 +583,14 @@ Contributing to Connexion/TODOs
 We welcome your ideas, issues, and pull requests. Just follow the
 usual/standard GitHub practices.
 
+For easy development, please install connexion in editable mode with the :code:`tests` extra, and
+install the pre-commit hooks.
+
+.. code-block:: bash
+
+    pip install -e .[tests]
+    pre-commit install
+
 You can find out more about how Connexion works and where to apply your changes by having a look
 at our `ARCHITECTURE.rst <ARCHITECTURE.rst>`_.
 
diff --git a/setup.py b/setup.py
index c7ec3e0..cc14c0c 100755
--- a/setup.py
+++ b/setup.py
@@ -39,10 +39,9 @@ flask_require = [
 ]
 
 tests_require = [
-    'decorator>=5,<6',
     'pytest>=6,<7',
+    'pre-commit>=2,<3',
     'pytest-cov>=2,<3',
-    'testfixtures>=6,<7',
     *flask_require,
     swagger_ui_require
 ]
@@ -92,7 +91,6 @@ setup(
     url='https://github.com/zalando/connexion',
     keywords='openapi oai swagger rest api oauth flask microservice framework',
     license='Apache License Version 2.0',
-    setup_requires=['flake8'],
     python_requires=">=3.6",
     install_requires=install_requires + flask_require,
     tests_require=tests_require,
diff --git a/tox.ini b/tox.ini
index 197650f..ad76253 100644
--- a/tox.ini
+++ b/tox.ini
@@ -9,10 +9,7 @@ envlist =
     {py38}-{min,pypi,dev}
     {py39}-{min,pypi,dev}
     {py310}-{min,pypi,dev}
-    isort-check
-    isort-check-examples
-    isort-check-tests
-    flake8
+    pre-commit
     mypy
 
 [gh-actions]
@@ -20,7 +17,7 @@ python =
     3.7: py37-min,py37-pypi
     3.8: py38-min,py38-pypi
     3.9: py39-min,py39-pypi
-    3.10: py310-min,py310-pypi,flake8,isort-check,isort-check-examples,isort-check-tests,mypy
+    3.10: py310-min,py310-pypi,pre-commit,mypy
 
 [testenv]
 setenv=PYTHONPATH = {toxinidir}:{toxinidir}
@@ -35,29 +32,9 @@ commands=
     dev: pip install --upgrade -r {toxworkdir}/requirements-dev.txt
     python setup.py test
 
-[testenv:flake8]
-deps=
-    flake8==3.9.2
-    flake8-rst-docstrings==0.2.3
-commands=python setup.py flake8
-
-[testenv:isort-check]
-basepython=python3
-deps=isort==5.9.1
-changedir={toxinidir}/connexion
-commands=isort --project connexion --check-only --diff .
-
-[testenv:isort-check-examples]
-basepython=python3
-deps=isort==5.9.1
-changedir={toxinidir}/examples
-commands=isort --thirdparty connexion --check-only --diff .
-
-[testenv:isort-check-tests]
-basepython=python3
-deps=isort==5.9.1
-changedir={toxinidir}/tests
-commands=isort --thirdparty connexion --check-only --diff .
+[testenv:pre-commit]
+deps=pre-commit
+commands=pre-commit run --all-files --show-diff-on-failure
 
 [testenv:mypy]
 deps=